Description

Cyclooctane-D16 is a fully deuterated isotopologue of cyclooctane, where all sixteen hydrogen atoms are replaced by deuterium (²H). This high isotopic purity makes it an essential internal standard and solvent for advanced analytical techniques, particularly Nuclear Magnetic Resonance (NMR) spectroscopy. It is a critical material for researchers and quality control laboratories in the pharmaceutical, chemical, and academic sectors requiring precise molecular analysis and solvent signal suppression.

Application

• NMR Spectroscopy Solvent: Primary application as a deuterated solvent for ¹H NMR, providing a non-interfering signal background for analyzing organic compounds.
• Internal Standard for Quantitative Analysis: Used in mass spectrometry (MS) and gas chromatography (GC) as a stable, isotopically labeled reference standard for accurate quantification.
• Mechanistic Studies & Kinetic Isotope Effects: Employed in research to study reaction mechanisms and kinetic isotope effects (KIE) due to the significant mass difference between C-H and C-D bonds.
• Polymer & Material Science Research: Acts as a probe molecule in studies of polymer dynamics, host-guest chemistry, and phase behavior in confined systems.
• Pharmaceutical Development: Utilized in the analysis and structural elucidation of active pharmaceutical ingredients (APIs) and complex natural products.
• Metabolic Tracing: Serves as a starting material or tracer in the synthesis of deuterated compounds for metabolic pathway studies in biological systems.

Basic Information

Product Name	Cyclooctane-D16
CAS No.	92204-03-0
Molecular Formula	C8D16
Molecular Weight	128.31 g/mol
Synonyms	Perdeuterocyclooctane; Cyclooctane-d16; Octadeuteriocyclooctane; [²H16]Cyclooctane; Cyclooctane (D16, 98%); Deuterated Cyclooctane; Cyclooctane-D16 (CAS 92204-03-0); 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8-Hexadecadeuteriocyclooctane
EINECS	Contact for details

Quality Control

Every batch of Cyclooctane-D16 is produced and analyzed under strict quality protocols to ensure exceptional isotopic and chemical purity. Our products undergo rigorous quality testing, including NMR and GC-MS analysis, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically ≥98 atom % D), chemical purity, and specific tests is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place away from heat and ignition sources. Due to its highly volatile nature, ensure containers are securely sealed and stored upright. Recommended storage temperature is 2-8°C to minimize evaporation and maintain stability.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (NMR)	Conforms to structure
Isotopic Purity (Atom % D)	≥ 98%
Chemical Purity (GC)	≥ 99.0%
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.