Description

2-Butanone, 1,3-Dihydroxy-4-(Phosphonooxy)-, (R)- is a chiral, phosphorylated derivative of a butanone sugar, representing a specialized biochemical intermediate of significant interest in advanced organic synthesis. This compound is valued for its role as a key building block in the development of complex molecules, particularly in pharmaceutical and agrochemical research where stereochemistry is critical. It is primarily sought by R&D chemists and process development scientists working on nucleotide analogs, prodrug development, and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of nucleotide analogs, antiviral agents, and other bioactive molecules requiring specific stereochemistry.
• Agrochemical Research: Used in the development of novel, targeted pesticides and herbicides where the phosphorylated moiety and chirality influence biological activity.
• Biochemical Probe Development: Serves as a precursor for labeled compounds or probes used in studying enzymatic pathways, particularly those involving kinases or phosphatases.
• Prodrug Synthesis: Employed in the design and synthesis of prodrugs, where the phosphate group can be utilized for improved bioavailability or targeted delivery.
• Academic & Industrial R&D: A valuable tool for synthetic organic chemists in universities and corporate labs exploring new chemical entities and reaction methodologies.

Basic Information

Product Name	2-Butanone, 1,3-Dihydroxy-4-(Phosphonooxy)-, (R)-
CAS No.	92175-70-7
Molecular Formula	C4H9O7P
Molecular Weight	200.09 g/mol
Synonyms	(R)-1,3-Dihydroxy-4-(phosphonooxy)butan-2-one; (R)-Glycerone 4-phosphate; (R)-Dihydroxyacetone phosphate (DHAP) analog; (R)-4-Phosphonooxy-1,3-dihydroxy-2-butanone; 92175-70-7; Phosphorylated (R)-butanone derivative
EINECS	Contact for details

Quality Control

Every batch of 2-Butanone, 1,3-Dihydroxy-4-(Phosphonooxy)-, (R)- is produced and controlled under a strict quality management system. We employ advanced analytical techniques, including chiral HPLC and NMR spectroscopy, to ensure high enantiomeric purity and chemical identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.