Description

4-Phenyl-5-Piperidin-1-Yl-4H-1,2,4-Triazole-3-Thiol is a specialized heterocyclic organic compound featuring a triazole core substituted with phenyl, piperidinyl, and thiol functional groups. This unique molecular architecture makes it a valuable intermediate for the synthesis of novel pharmacologically active agents, particularly in medicinal chemistry research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: Key building block for the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or infectious diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and combinatorial chemistry libraries to explore new bioactive chemical space.
• Agrochemical Synthesis: Serves as a precursor in the development of novel fungicides, herbicides, or plant growth regulators.
• Ligand in Coordination Chemistry: The thiol and nitrogen donor atoms can act as chelating agents for metal ions, useful in catalysis or material science.
• Chemical Biology Probe Development: Utilized to create molecular tools for studying enzyme function or protein interactions within biological systems.

Basic Information

Product Name	4-Phenyl-5-Piperidin-1-Yl-4H-1,2,4-Triazole-3-Thiol
CAS No.	92110-77-5
Molecular Formula	C13H16N4S
Molecular Weight	260.36 g/mol
Synonyms	4-Phenyl-5-(piperidin-1-yl)-4H-1,2,4-triazole-3-thiol; 5-(1-Piperidinyl)-4-phenyl-4H-1,2,4-triazole-3-thiol; 4-Phenyl-5-(1-piperidinyl)-1,2,4-triazole-3-thiol; 3-Mercapto-4-phenyl-5-(1-piperidinyl)-1,2,4-triazole; 92110-77-5; 4-Phenyl-5-piperidino-4H-1,2,4-triazole-3-thiol
EINECS	Contact for details

Quality Control

Our production of 4-Phenyl-5-Piperidin-1-Yl-4H-1,2,4-Triazole-3-Thiol adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity, critical for sensitive R&D and scale-up processes. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.