Description

Butanoic Acid, 3-[(tert-Butyldimethylsilyl)Oxy]-, tert-Butyldimethylsilyl Ester is a specialized silyl-protected derivative of 3-hydroxybutanoic acid, designed for advanced synthetic chemistry. This compound is a critical reagent for the protection of hydroxyl groups, offering exceptional stability under a wide range of reaction conditions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of complex organic molecules, including active pharmaceutical ingredients (APIs) and natural products.

Application

• Pharmaceutical Intermediate Synthesis: Key building block for the production of chiral drugs and complex bioactive molecules.
• Peptide and Carbohydrate Chemistry: Used as a protecting group for hydroxyl functionalities during multi-step syntheses.
• Agrochemical Research: Intermediate in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Precursor: Serves as a monomer or modifier in the synthesis of specialized polymers and coatings.
• Asymmetric Synthesis: Employed in stereoselective reactions to construct molecules with defined three-dimensional structures.
• Process Chemistry Development: Valued for its robustness in scaling up laboratory syntheses to commercial manufacturing processes.

Basic Information

Product Name	Butanoic Acid, 3-[(tert-Butyldimethylsilyl)Oxy]-, tert-Butyldimethylsilyl Ester
CAS No.	91998-39-9
Molecular Formula	C14H30O3Si2
Molecular Weight	302.56 g/mol
Synonyms	3-[(tert-Butyldimethylsilyl)oxy]butanoic acid tert-butyldimethylsilyl ester; 3-(TBDMS-oxy)butyric acid TBDMS ester; 3-(tert-Butyldimethylsiloxy)butyric acid tert-butyldimethylsilyl ester; TBDMS 3-hydroxybutyrate TBDMS ether; 3-Hydroxybutanoic acid, bis(TBDMS) derivative; 3-O-TBDMS Butanoic Acid TBDMS Ester; Silyl-protected 3-hydroxybutyrate
EINECS	Contact for details

Quality Control

Our production of Butanoic Acid, 3-[(tert-Butyldimethylsilyl)Oxy]-, tert-Butyldimethylsilyl Ester adheres to stringent quality management protocols. Each batch is analyzed to ensure high chemical purity and consistency, meeting the exacting standards required for research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We support compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC or HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.