Description

4,4',4''-Tris(4,5-Dichlorophthalimido)Trityl Bromide is a specialized brominated trityl protecting group reagent, distinguished by its three dichlorophthalimide substituents which enhance its stability and reactivity profile. This compound is critically important for advanced organic synthesis, particularly in the preparation of complex molecules where selective protection and deprotection of functional groups is required. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and intermediates.

Application

• Solid-Phase Peptide Synthesis (SPPS): Used as a robust protecting group for amino acids, especially in the synthesis of challenging peptide sequences.
• Oligonucleotide and Nucleoside Chemistry: Employed for the protection of exocyclic amino groups in nucleosides during the synthesis of DNA/RNA analogs and antisense oligonucleotides.
• Pharmaceutical Intermediate Manufacturing: Serves as a key building block in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Applied in the development of novel herbicides, fungicides, and insecticides requiring sophisticated molecular architectures.
• Polymer and Material Science: Acts as a functional monomer or cross-linking agent in the creation of specialty polymers with tailored properties.
• Chemical Biology Probes: Utilized in the design and synthesis of labeled probes for studying biological mechanisms and interactions.

Basic Information

Item	Details
Product Name	4,4',4''-Tris(4,5-Dichlorophthalimido)Trityl Bromide
CAS No.	91898-93-0
Molecular Formula	C51H21BrCl6N3O6
Molecular Weight	1080.31 g/mol
Synonyms	Tris(4,5-dichlorophthalimido)trityl bromide; 4,4',4''-Tris(N-4,5-dichlorophthalimido)trityl bromide; Bromotris(4,5-dichloro-1,3-dioxoisoindol-2-yl)phenylmethane; Trt(Br)-Im(DC)3; DCPITrt-Br; 2,2',2''-(((Bromophenyl)methylene)tris(4,5-dichloro-1H-isoindole-1,3(2H)-dione)); Bromo-tris-(4,5-dichloro-phthalimido)-triphenylmethane
EINECS	Contact for details

Quality Control

Our 4,4',4''-Tris(4,5-Dichlorophthalimido)Trityl Bromide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.