Description

5-Bromo-n-(2-(Dimethylamino)Ethyl)-1H-Indazole-3-Carboxamide is a high-purity, advanced pharmaceutical intermediate characterized by its unique indazole core structure. This compound matters for its critical role as a key building block in the synthesis of novel, targeted therapeutic agents, particularly in oncology and neurological research. Pharmaceutical R&D laboratories and fine chemical manufacturers need this material to develop and scale up production of innovative drug candidates, where consistent quality and reliable supply are paramount.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of potent kinase inhibitors and other targeted small-molecule drugs.
• Oncology Research: Used in the development of novel anti-cancer compounds that target specific cellular pathways.
• Neurological Disorder Research: Acts as a key scaffold for creating compounds aimed at treating CNS-related conditions.
• Chemical Biology: Employed as a molecular probe to study enzyme function and protein interactions within biological systems.
• Process Chemistry & Scale-Up: Utilized in route scouting and optimization for the commercial manufacturing of active pharmaceutical ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global drug discovery and development pipelines.

Basic Information

Product Name	5-Bromo-n-(2-(Dimethylamino)Ethyl)-1H-Indazole-3-Carboxamide
CAS No.	91766-59-5
Molecular Formula	C₁₄H₁₉BrN₄O
Molecular Weight	339.23 g/mol
Synonyms	5-Bromo-N-[2-(dimethylamino)ethyl]-1H-indazole-3-carboxamide; 5-Bromo-1H-indazole-3-carboxylic acid (2-(dimethylamino)ethyl)amide; 91766-59-5; UNII-2Q6Q2OQ2JN; 2Q6Q2OQ2JN; CHEMBL3186663; BDBM50111073; AKOS015915976
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-n-(2-(Dimethylamino)Ethyl)-1H-Indazole-3-Carboxamide is manufactured under strict quality management systems. Our products undergo rigorous quality testing using advanced analytical techniques (HPLC, GC-MS, NMR) to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.