Description

Methyl 2-(1,2,3,4-Tetrahydro-1-Isoquinolinyl)-Acetate is a versatile heterocyclic building block and synthetic intermediate of significant interest in advanced organic synthesis. Its core value lies in its functionalized tetrahydroisoquinoline scaffold, which is a privileged structure in medicinal chemistry, enabling the efficient construction of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly those developing new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of tetrahydroisoquinoline-based drug candidates, including potential central nervous system (CNS) agents, antimicrobials, and cardiovascular drugs.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides that incorporate the tetrahydroisoquinoline moiety for enhanced biological activity.
• Organic Synthesis & Catalysis: Serves as a valuable precursor or ligand in asymmetric synthesis and catalytic reactions due to its chiral nitrogen center.
• Academic & R&D Laboratories: Employed in methodological studies and the discovery of new chemical entities (NCEs) within medicinal and synthetic chemistry programs.
• Fine Chemical Production: Integral in the multi-step synthesis of specialty chemicals, dyes, and advanced materials requiring complex heterocyclic frameworks.

Basic Information

Product Name	Methyl 2-(1,2,3,4-Tetrahydro-1-Isoquinolinyl)-Acetate
CAS No.	91640-73-2
Molecular Formula	C₁₂H₁₅NO₂
Molecular Weight	205.25 g/mol
Synonyms	Methyl (1,2,3,4-tetrahydro-1-isoquinolinyl)acetate; 2-(1,2,3,4-Tetrahydro-1-isoquinolinyl)acetic acid methyl ester; 1,2,3,4-Tetrahydro-1-isoquinolineacetic acid methyl ester; Methyl 1,2,3,4-tetrahydroisoquinoline-1-acetate; 1-Carbomethoxymethyl-1,2,3,4-tetrahydroisoquinoline; NSC 339063; Methyl 2-(1,2,3,4-tetrahydroisoquinolin-1-yl)acetate
EINECS	Contact for details

Quality Control

Our Methyl 2-(1,2,3,4-Tetrahydro-1-Isoquinolinyl)-Acetate is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and scale-up applications. We provide comprehensive analytical data, including HPLC/GC purity, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) detailing all specifications is available for every batch upon request, supporting your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.