Description

3-Thiophenecarbonyl Chloride, 5-Nitro- (9Ci) is a specialized heterocyclic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the reactive carbonyl chloride group and the electron-withdrawing nitro substituent, which enable precise functionalization and the construction of complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors, particularly for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging the thiophene scaffold for bioactivity.
• Functional Material Production: Serves as a monomer or coupling agent in the creation of conductive polymers, organic semiconductors, and specialty dyes.
• Ligand and Catalyst Development: Employed to synthesize complex chelating ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A versatile reagent for academic and industrial R&D focused on heterocyclic chemistry and molecular design.

Basic Information

Product Name	3-Thiophenecarbonyl Chloride, 5-Nitro- (9Ci)
CAS No.	91538-55-5
Molecular Formula	C5H2ClNO3S
Molecular Weight	191.59 g/mol
Synonyms	5-Nitro-3-thiophenecarbonyl chloride; 5-Nitrothiophene-3-carbonyl chloride; 3-Carbonylchloride-5-nitrothiophene; 5-Nitro-3-thienoyl chloride; 5-Nitrothiophene-3-carboxylic acid chloride; 3-Thienoyl chloride, 5-nitro-; 91538-55-5
EINECS	Contact for details

Quality Control

Our 3-Thiophenecarbonyl Chloride, 5-Nitro- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 96.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.