Description

(9α,13α)-17-(Cyclopropylmethyl)-4,5β-Epoxy-3,14α-Dihydroxymorphinan-6-One CAS NO 91464-13-0 is a high-purity, synthetic opioid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and analytical study of potent analgesic agents. It is primarily utilized by pharmaceutical R&D laboratories and contract research organizations (CROs) focused on neuropharmacology and pain management. Our supply ensures the consistency and reliability required for sensitive preclinical and analytical applications.

Application

• Pharmaceutical Reference Standard: Used as a high-purity calibrant in analytical methods (HPLC, GC-MS) for quality control and forensic analysis.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a key synthetic building block in the research-scale production of specialized opioid analgesics.
• Biochemical Research: Employed in in-vitro studies to investigate opioid receptor (MOR, DOR, KOR) binding affinity, selectivity, and functional activity.
• Metabolite Studies: Utilized as a precursor or standard in the identification and quantification of drug metabolites during pharmacokinetic research.
• Method Development & Validation: Critical for developing and validating sensitive analytical assays in regulatory and clinical trial support.

Basic Information

Product Name	(9α,13α)-17-(Cyclopropylmethyl)-4,5β-Epoxy-3,14α-Dihydroxymorphinan-6-One
CAS No.	91464-13-0
Molecular Formula	C₂₂H₂₇NO₄
Molecular Weight	369.46 g/mol
Synonyms	Cyclopropylmethylnormorphinone; 6-Oxo-17-(cyclopropylmethyl)-4,5α-epoxy-3,14α-dihydroxymorphinan; 17-Cyclopropylmethyl-4,5α-epoxymorphinan-3,6α,14-triol-6-one; 6-Oxocyclopropylmethylnormorphine; 17-Cyclopropylmethyl-6-oxonormorphine; CPNMO; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of (9α,13α)-17-(Cyclopropylmethyl)-4,5β-Epoxy-3,14α-Dihydroxymorphinan-6-One is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to guarantee traceability and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.