Description

trans-Cinnamic-Beta 2 3 4 5 6-D6 Acid is a high-purity, isotopically labeled derivative of cinnamic acid, where six deuterium atoms are incorporated at specific positions on the aromatic ring. This compound is essential for advanced analytical and research applications requiring precise internal standards and metabolic pathway tracing. It is primarily utilized by pharmaceutical researchers, analytical chemists, and agrochemical developers working in drug discovery, pharmacokinetic studies, and environmental fate analysis.

Application

• Internal Standard for Mass Spectrometry (MS): Provides unmatched accuracy in quantitative analysis (LC-MS, GC-MS) for cinnamic acid and related metabolites in complex biological matrices.
• Drug Metabolism and Pharmacokinetics (DMPK): Enables precise tracking of drug absorption, distribution, metabolism, and excretion (ADME) studies for compounds containing the cinnamic acid moiety.
• Biochemical Pathway Analysis: Used as a tracer to elucidate biosynthetic pathways in plants, such as the phenylpropanoid pathway leading to flavonoids and lignin.
• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for method development, validation, and quality control in pharmaceutical laboratories.
• Environmental Analysis: Facilitates the detection and quantification of cinnamic acid derivatives in environmental samples with high sensitivity and reduced matrix interference.
• Synthesis of Labeled Compounds: Acts as a key building block for the synthesis of more complex deuterated molecules for research and development.

Basic Information

Product Name	trans-Cinnamic-Beta 2 3 4 5 6-D6 Acid
CAS No.	91453-04-2
Molecular Formula	C9D6H2O2
Molecular Weight	154.20 g/mol
Synonyms	(E)-3-(2,3,4,5,6-Pentadeuteriophenyl)-2-propenoic Acid; trans-3-(2,3,4,5,6-Pentadeuteriophenyl)acrylic Acid; (E)-Cinnamic-2,3,4,5,6-d5 Acid; Cinnamic Acid-d6 (aromatic-d5); β-Deuterated Cinnamic Acid; Isotopic Labeled Cinnamic Acid; Deuterated Internal Standard for Cinnamic Acid
EINECS	Contact for details

Quality Control

Every batch of trans-Cinnamic-Beta 2 3 4 5 6-D6 Acid is produced and analyzed under strict quality management protocols to ensure the highest isotopic and chemical purity for critical research applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing isotopic enrichment, chemical purity, and analytical methods (NMR, MS, HPLC) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a cool, dry, and well-ventilated place. This product is hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (MS)	≥ 98 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.