Description

1H-Benzimidazole, 2-Phenyl-5-(Trifluoromethyl)- is a high-value trifluoromethylated benzimidazole derivative, a privileged scaffold in modern medicinal and agrochemical chemistry. Its core structure is engineered to enhance molecular stability, bioavailability, and binding affinity in target interactions. This compound is primarily sought after by research and development chemists in the pharmaceutical and crop protection industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the development of new drug candidates, particularly in oncology, antiviral, and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced fungicides, herbicides, and insecticides, where the trifluoromethyl group improves efficacy and environmental profile.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for catalysts or components in organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Utilized in the design of molecular probes and inhibitors to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	1H-Benzimidazole, 2-Phenyl-5-(Trifluoromethyl)-
CAS No.	91437-85-3
Molecular Formula	C14H9F3N2
Molecular Weight	262.23 g/mol
Synonyms	2-Phenyl-5-(trifluoromethyl)-1H-benzimidazole; 5-(Trifluoromethyl)-2-phenylbenzimidazole; 2-Phenyl-5-trifluoromethylbenzimidazole; 1H-Benzimidazole, 2-phenyl-5-(trifluoromethyl)-; 91437-85-3; 2-Phenyl-5-(trifluoromethyl)benzimidazole; 5-Trifluoromethyl-2-phenyl-1H-benzimidazole
EINECS	Contact for details

Quality Control

Our 1H-Benzimidazole, 2-Phenyl-5-(Trifluoromethyl)- is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.