Description

Methyl-D3 Methanesulfonate is a deuterated isotopologue of methyl methanesulfonate, a versatile alkylating agent. This compound is specifically valued for its use as a stable isotope-labeled internal standard in quantitative mass spectrometry, ensuring analytical accuracy and reliability. It is essential for researchers and quality control laboratories in the pharmaceutical, agrochemical, and advanced material sectors who require precise quantification and metabolic studies.

Application

• Internal Standard for LC-MS/MS: Critical for the accurate quantification of methyl methanesulfonate and related compounds in pharmaceutical impurity profiling and residual solvent analysis.
• Metabolic Pathway Tracing: Used in deuterium labeling studies to investigate biochemical mechanisms and metabolic fate in pharmacological and toxicological research.
• Analytical Method Development: Serves as a key reference material for developing and validating sensitive chromatographic and spectrometric methods.
• Deuterated Building Block: Employed in organic synthesis for the preparation of deuterium-labeled target molecules for research and development.
• Quality Assurance & Control: Supports GMP-compliant testing in pharmaceutical manufacturing to monitor and control genotoxic impurities.

Basic Information

Product Name	Methyl-D3 Methanesulfonate
CAS No.	91419-94-2
Molecular Formula	C2D3HO3S
Molecular Weight	112.13 g/mol
Synonyms	Deuterated Methyl Methanesulfonate; Methyl-d3 Methanesulfonate; Methanesulfonic-d3 Acid Methyl Ester; MMS-d3; (2H3)Methyl Methanesulfonate; Methyl-d3 Ester of Methanesulfonic Acid; CD3OSO2CH3; Methyl-d3 Mesylate
EINECS	Contact for details

Quality Control

Our Methyl-D3 Methanesulfonate is produced and handled under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR and mass spectrometry, to confirm isotopic purity and chemical identity. A detailed Certificate of Analysis (COA) is provided, documenting assay, isotopic enrichment, and impurity profiles to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the product should be handled under an inert atmosphere or in a controlled environment to prevent moisture absorption. Recommended long-term storage at 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (NMR/MS)	≥ 99.0 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.