Description

3,4-Dimethoxy[7-13C]-Benzyl Alcohol is a stable isotope-labeled derivative of veratryl alcohol, where the carbon-13 (13C) isotope is specifically incorporated at the 7-position of the benzyl ring. This compound is essential as a high-purity internal standard and tracer in quantitative mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy, providing unparalleled accuracy for metabolic and pharmacokinetic studies. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in advanced analytical chemistry and drug development.

Application

• Quantitative Mass Spectrometry (MS): Serves as a critical internal standard for the precise quantification of veratryl alcohol and related metabolites in complex biological matrices, eliminating matrix effects and improving data reliability.
• Nuclear Magnetic Resonance (NMR) Spectroscopy: Used as a 13C-labeled tracer to elucidate metabolic pathways and reaction mechanisms, providing clear spectral tracking of the labeled carbon atom.
• Pharmaceutical Drug Metabolism and Pharmacokinetics (DMPK) Studies: Enables accurate tracking of drug absorption, distribution, metabolism, and excretion (ADME) for veratryl alcohol-based compounds or analogs.
• Biochemical Research: Facilitates studies on lignin biodegradation and fungal enzyme systems where veratryl alcohol is a key intermediate or mediator.
• Stable Isotope Labeling: Acts as a building block for the synthesis of more complex 13C-labeled compounds for use in various research applications.
• Quality Control & Method Development: Employed in analytical laboratories to develop, validate, and ensure the accuracy of chromatographic and spectroscopic methods.

Basic Information

Product Name	3,4-Dimethoxy[7-13C]-Benzyl Alcohol
CAS No.	91384-88-2
Molecular Formula	C9H1213CO3
Molecular Weight	169.19 g/mol (for 13C1 labeled form)
Synonyms	[7-13C]-3,4-Dimethoxybenzyl Alcohol; 13C-Labeled Veratryl Alcohol; 4-(Hydroxymethyl)-1,2-dimethoxy[7-13C]benzene; 3,4-Dimethoxy(13C)benzyl Alcohol; Veratryl-7-13C Alcohol; 1-(3,4-Dimethoxyphenyl)[7-13C]methanol; 3,4-Dimethoxybenzenemethanol-7-13C; Isotopically Labeled Veratryl Alcohol
EINECS	Contact for details

Quality Control

Every batch of our 3,4-Dimethoxy[7-13C]-Benzyl Alcohol is manufactured and analyzed under strict quality management systems. The product undergoes rigorous testing, including isotopic enrichment analysis by NMR and MS, chemical purity assessment by HPLC, and identity confirmation by IR spectroscopy, to ensure it meets the exacting standards required for analytical and research applications. A comprehensive Certificate of Analysis (COA) detailing isotopic purity, chemical purity, and all analytical results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability and isotopic integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Isotopic Enrichment	≥ 99 atom % 13C
Chemical Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 99%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.