Description

4-Chloro-2-Phenyl-7H-Pyrrolo[2,3-D]Pyrimidine is a high-value heterocyclic building block and pharmaceutical intermediate. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of kinase inhibitors and other targeted therapeutics. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Serves as a precursor for developing labeled probes or active compounds for biological target validation.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals and advanced materials.
• Academic Research: Utilized in university and institutional labs for methodological development in organic synthesis and heterocyclic chemistry.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting outsourced drug discovery and development projects.

Basic Information

Product Name	4-Chloro-2-Phenyl-7H-Pyrrolo[2,3-D]Pyrimidine
CAS No.	91331-36-1
Molecular Formula	C₁₂H₈ClN₃
Molecular Weight	229.66 g/mol
Synonyms	4-Chloro-2-phenyl-7H-pyrrolo[2,3-d]pyrimidine; 2-Phenyl-4-chloro-7H-pyrrolo[2,3-d]pyrimidine; 4-Chloro-2-phenyl-7H-pyrrolo[2,3-d]pyrimidine; 7H-Pyrrolo[2,3-d]pyrimidine, 4-chloro-2-phenyl-; 91331-36-1; 4-Chloro-2-phenylpyrrolo[2,3-d]pyrimidine; Pyrrolo[2,3-d]pyrimidine, 4-chloro-2-phenyl-7H-
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Phenyl-7H-Pyrrolo[2,3-D]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.