Description

1-(Chloromethyl)-4-Phenyl-3,4-Dihydroisoquinoline Hydrochloride is a high-purity, specialized organic intermediate of significant importance in advanced chemical synthesis. This compound matters for its role as a key building block in the development of complex heterocyclic molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active ingredients and exploring new chemical entities.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel isoquinoline-based drug candidates, including potential central nervous system (CNS) agents and kinase inhibitors.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides with complex heterocyclic scaffolds.
• Fine Chemical Synthesis: Used in the multi-step synthesis of specialty chemicals, dyes, and advanced materials requiring the 3,4-dihydroisoquinoline core structure.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the exploration of new chemical reactions involving chloromethyl and dihydroisoquinoline functionalities.
• Chemical Library Development: A valuable scaffold for creating diverse compound libraries for high-throughput screening in drug discovery programs.

Basic Information

Product Name	1-(Chloromethyl)-4-Phenyl-3,4-Dihydroisoquinoline Hydrochloride
CAS No.	91123-65-8
Molecular Formula	C17H16ClN•HCl
Molecular Weight	306.23 g/mol
Synonyms	1-(Chloromethyl)-4-phenyl-3,4-dihydroisoquinoline hydrochloride; 4-Phenyl-1-(chloromethyl)-3,4-dihydroisoquinoline HCl; 1-(Chloromethyl)-4-phenyl-1,2,3,4-tetrahydroisoquinoline hydrochloride; 91123-65-8; 4-Phenyl-1-(chloromethyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride; 1-(Chloromethyl)-4-phenyl-3,4-dihydro-isoquinoline hydrochloride; 4-Phenyl-1-chloromethyl-3,4-dihydroisoquinoline hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(Chloromethyl)-4-Phenyl-3,4-Dihydroisoquinoline Hydrochloride is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.