Description

Ethyl 6-Nitro-1H-Indole-3-Carboxylate is a versatile nitro-substituted indole derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a functionalized indole scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for chemists and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity building blocks for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging the bioactivity of the indole core.
• Organic Synthesis Building Block: Employed in heterocyclic and medicinal chemistry for the construction of complex indole-based libraries via further functionalization of the nitro and ester groups.
• Material Science Research: Investigated as a monomer or functional component in the development of advanced organic electronic materials and dyes.
• Academic & R&D Laboratories: Serves as a standard reagent for methodological studies in nitration, esterification, and indole chemistry.

Basic Information

Product Name	Ethyl 6-Nitro-1H-Indole-3-Carboxylate
CAS No.	91090-95-8
Molecular Formula	C11H10N2O4
Molecular Weight	234.21 g/mol
Synonyms	6-Nitro-1H-indole-3-carboxylic acid ethyl ester; Ethyl 6-nitroindole-3-carboxylate; 1H-Indole-3-carboxylic acid, 6-nitro-, ethyl ester; 6-Nitroindole-3-carboxylic Acid Ethyl Ester; 3-Carbethoxy-6-nitroindole; Ethyl 6-nitro-1H-indole-3-carboxylate; 91090-95-8
EINECS	Contact for details

Quality Control

Our Ethyl 6-Nitro-1H-Indole-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.