Description

Ethyl 3-Amino-5-(4-Nitrophenyl)Thiophene-2-carboxylate is a high-purity, specialized organic intermediate of significant importance in advanced chemical synthesis. Its molecular structure, featuring both amino and nitrophenyl substituents on a thiophene core, makes it a valuable building block for creating complex heterocyclic compounds. This product is essential for research and development chemists and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science Research: Serves as a monomer or building block for the development of advanced organic electronic materials, such as organic semiconductors and conductive polymers.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized dyes and pigments due to the presence of the chromophoric nitrophenyl group.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and process chemistry for creating libraries of novel compounds.
• Custom Synthesis: Used by contract research and manufacturing organizations (CROs/CMOs) for client-specific projects requiring complex thiophene derivatives.

Basic Information

Product Name	Ethyl 3-Amino-5-(4-Nitrophenyl)Thiophene-2-carboxylate
CAS No.	91077-00-8
Molecular Formula	C13H12N2O4S
Molecular Weight	292.31 g/mol
Synonyms	Ethyl 3-Amino-5-(4-Nitrophenyl)Thiophene-2-carboxylate; 3-Amino-5-(4-nitrophenyl)thiophene-2-carboxylic acid ethyl ester; Ethyl 3-amino-5-(p-nitrophenyl)thiophene-2-carboxylate; 2-Thiophenecarboxylic acid, 3-amino-5-(4-nitrophenyl)-, ethyl ester; 91077-00-8; Ethyl 3-amino-5-(4'-nitrophenyl)thiophene-2-carboxylate
EINECS	Contact for details

Quality Control

Every batch of Ethyl 3-Amino-5-(4-Nitrophenyl)Thiophene-2-carboxylate is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and should be stored away from light. It is also easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.