Description

3-Amino-5-Biphenyl-4-Yl-Thiophene-2-Carboxylic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its unique thiophene-biphenyl hybrid structure. This compound is critical for the synthesis of complex organic molecules, offering a versatile scaffold for medicinal chemistry research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in the development of novel herbicides and fungicides, leveraging its heterocyclic core for bioactivity.
• Material Science Precursor: Serves as a monomer or precursor for organic electronic materials, such as conductive polymers and organic semiconductors.
• Dye & Pigment Synthesis: Employed in the creation of specialized dyes and pigments due to its conjugated system and amino functionality.
• Academic & Contract Research: Essential for academic research in organic synthesis methodology and for CROs (Contract Research Organizations) conducting client-specific projects.

Basic Information

Product Name	3-Amino-5-Biphenyl-4-Yl-Thiophene-2-Carboxylic Acid Methyl Ester
CAS No.	91076-97-0
Molecular Formula	C18H15NO2S
Molecular Weight	309.38 g/mol
Synonyms	Methyl 3-amino-5-(biphenyl-4-yl)thiophene-2-carboxylate; 3-Amino-5-(4-phenylphenyl)thiophene-2-carboxylic acid methyl ester; 3-Amino-5-(1,1'-biphenyl-4-yl)-2-thiophenecarboxylic acid methyl ester; 91076-97-0; 5-(Biphenyl-4-yl)-3-aminothiophene-2-carboxylic acid methyl ester; Methyl 5-(4-phenylphenyl)-3-aminothiophene-2-carboxylate; 3-Amino-5-(4-phenylphenyl)-2-thiophenecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 3-Amino-5-Biphenyl-4-Yl-Thiophene-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to brown powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.