Description

3-Amino-5-(4-Bromophenyl)Thiophene-2-Carboxylic Acid Methyl Ester is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its molecular structure, featuring both an amino group and a bromophenyl substituent on a thiophene core, makes it a critical intermediate for constructing complex molecules with tailored electronic and biological properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Research: Used to develop novel herbicides, fungicides, and insecticides by serving as a core scaffold for bioactive molecules.
• Material Science: Acts as a monomer or building block for conductive polymers, organic semiconductors, and non-linear optical (NLO) materials due to the electron-rich thiophene system.
• Chemical Synthesis: Utilized in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and other transformations to introduce complex molecular fragments.
• Dye & Pigment Industry: Serves as an intermediate for synthesizing specialized dyes and pigments with specific light-absorption properties.

Basic Information

Item	Details
Product Name	3-Amino-5-(4-Bromophenyl)Thiophene-2-Carboxylic Acid Methyl Ester
CAS No.	91076-95-8
Molecular Formula	C12H10BrNO2S
Molecular Weight	312.18 g/mol
Synonyms	Methyl 3-amino-5-(4-bromophenyl)thiophene-2-carboxylate; 3-Amino-5-(p-bromophenyl)thiophene-2-carboxylic acid methyl ester; 2-Thiophenecarboxylic acid, 3-amino-5-(4-bromophenyl)-, methyl ester; 91076-95-8; Methyl 3-amino-5-(4-bromophenyl)-2-thiophenecarboxylate; 5-(4-Bromophenyl)-3-aminothiophene-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 3-Amino-5-(4-Bromophenyl)Thiophene-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.