Description

Methyl 3-Amino-5-(4-Chlorophenyl)Thiophene-2-Carboxylate is a high-purity, functionalized thiophene derivative serving as a critical advanced intermediate in organic synthesis. Its molecular architecture, featuring both an amino group and a chlorophenyl substituent on the thiophene core, makes it a versatile building block for constructing complex heterocyclic systems. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiophene scaffold.
• Material Science Research: Serves as a monomer or functional unit in the development of conductive polymers, organic semiconductors, and non-linear optical (NLO) materials.
• Chemical Biology & Proteomics: Employed as a tagging or linking agent for bioconjugation and the development of chemical probes.
• Dye & Pigment Industry: Acts as an intermediate for synthesizing specialized dyes and pigments with specific light-absorption properties.
• Academic & Contract Research: A valuable reagent for methodological development and exploration of new synthetic pathways in heterocyclic chemistry.

Basic Information

Product Name	Methyl 3-Amino-5-(4-Chlorophenyl)Thiophene-2-Carboxylate
CAS No.	91076-93-6
Molecular Formula	C12H10ClNO2S
Molecular Weight	267.73 g/mol
Synonyms	Methyl 3-amino-5-(4-chlorophenyl)thiophene-2-carboxylate; 3-Amino-5-(4-chlorophenyl)thiophene-2-carboxylic acid methyl ester; Methyl 5-(4-chlorophenyl)-3-aminothiophene-2-carboxylate; 2-Thiophenecarboxylic acid, 3-amino-5-(4-chlorophenyl)-, methyl ester; 91076-93-6; 5-(4-Chlorophenyl)-3-aminothiophene-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 3-Amino-5-(4-Chlorophenyl)Thiophene-2-Carboxylate adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Quality is verified through modern analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment, supporting your quality management systems and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.