Description

(5-Nitrothiophen-2-Yl)Methanamine CAS NO 90993-47-8 is a high-purity, functionalized heterocyclic amine building block of significant importance in advanced organic synthesis. Its core value lies in the strategic combination of a nitro group and an amine moiety on a thiophene scaffold, enabling the construction of complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries who require reliable, high-quality intermediates for drug discovery and active ingredient development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, infectious diseases, and oncology.
• Agrochemical Synthesis: Serves as a versatile building block for developing new herbicides, fungicides, and insecticides, leveraging the bioactivity of the nitro-thiophene structure.
• Material Science Research: Used in the development of advanced organic electronic materials, such as conductive polymers and non-linear optical (NLO) materials, due to the electron-accepting nitro group and electron-donating potential of the thiophene ring.
• Ligand and Catalyst Development: The amine functionality allows for its use in creating novel chelating ligands for metal catalysis and organocatalysts for asymmetric synthesis.
• Dye and Pigment Chemistry: Acts as an intermediate in the production of specialized dyes and pigments where the nitro-thiophene unit contributes to color and stability properties.

Basic Information

Product Name	(5-Nitrothiophen-2-Yl)Methanamine
CAS No.	90993-47-8
Molecular Formula	C5H6N2O2S
Molecular Weight	158.18 g/mol
Synonyms	2-(Aminomethyl)-5-nitrothiophene; 5-Nitro-2-thiophenemethylamine; (5-Nitro-2-thienyl)methanamine; 2-Aminomethyl-5-nitrothiophene; 5-Nitrothiophene-2-methanamine; 5-Nitro-2-thiophenemethanamine; 5-Nitro-2-thienylmethylamine; 2-Thiophenemethanamine, 5-nitro-
EINECS	Contact for details

Quality Control

Every batch of (5-Nitrothiophen-2-Yl)Methanamine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.