Description

Acetic Anhydride (1,1'-13C2) is a stable isotope-labeled derivative of acetic anhydride, where two carbon atoms at the 1 and 1' positions are the carbon-13 isotope. This compound is essential for advanced analytical research, providing a critical internal standard and tracer for precise quantitative analysis and metabolic pathway studies using techniques like NMR and mass spectrometry. It is primarily utilized by research scientists and quality control laboratories in the pharmaceutical, agrochemical, and academic sectors for method development, validation, and complex biochemical investigations.

Application

• Internal Standard for Quantitative Analysis: Used in Gas Chromatography-Mass Spectrometry (GC-MS) and Liquid Chromatography-Mass Spectrometry (LC-MS) for accurate quantification of acetic anhydride or related compounds in complex matrices.
• Metabolic Pathway Tracing: Serves as a stable isotope tracer in biochemical and pharmacological research to study acetylation reactions, drug metabolism, and biosynthetic pathways.
• NMR Spectroscopy: Provides a distinct spectroscopic signature in Nuclear Magnetic Resonance (NMR) studies for structural elucidation and reaction monitoring.
• Pharmaceutical Impurity Profiling: Employed in the development and validation of analytical methods to identify and quantify impurities and degradants in Active Pharmaceutical Ingredients (APIs).
• Synthesis of Labeled Compounds: Acts as a key reagent for introducing carbon-13 labels into target molecules via acetylation reactions for subsequent research.
• Environmental and Food Safety Testing: Enhances the accuracy and reliability of analytical methods for detecting contaminants and residues.

Basic Information

Product Name	Acetic Anhydride (1,1'-13C2)
CAS No.	90980-78-2
Molecular Formula	(13CH3CO)2O
Molecular Weight	104.06 g/mol
Synonyms	Acetic-1,1'-13C2 Anhydride; (13C2)Acetic Anhydride; Ethanoic-1,1'-13C2 Anhydride; Acetyl-13C2 Oxide; Bis(acetyl-13C2) Oxide; 13C Labeled Acetic Anhydride; Isotopic Acetic Anhydride; [1,1'-13C2]Acetic Anhydride
EINECS	Contact for details

Quality Control

Every batch of our Acetic Anhydride (1,1'-13C2) is manufactured and analyzed under strict quality management systems. We guarantee high chemical and isotopic purity, with comprehensive testing performed using advanced analytical techniques including NMR, GC-MS, and IR spectroscopy. A detailed Certificate of Analysis (COA), specifying assay, isotopic enrichment, and impurity profiles, is provided with each shipment to ensure traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases, amines, and oxidizing agents. Due to its nature as a strong acid/organic solvent, appropriate secondary containment is recommended. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.