Description

Butyryl-2,2-D2 Chloride is a deuterated derivative of butyryl chloride, a key acylating agent used in organic synthesis. This compound is specifically valued for its role as a stable isotope-labeled reagent, enabling advanced research and development in analytical chemistry and pharmacology. It is essential for scientists and manufacturers in the pharmaceutical, agrochemical, and material science industries who require precise deuterium labeling for metabolic studies, tracer applications, and the synthesis of novel compounds.

Application

• Deuterium-Labeled Intermediate Synthesis: A key building block for introducing deuterium atoms into target molecules for pharmaceutical and agrochemical research.
• Metabolic Pathway Tracing: Used in the preparation of internal standards and tracers for mass spectrometry (MS) and nuclear magnetic resonance (NMR) studies to elucidate drug metabolism.
• Active Pharmaceutical Ingredient (API) Development: Employed in the synthesis of deuterated drug candidates, which can offer improved metabolic stability and pharmacokinetic profiles.
• Polymer and Material Science: Serves as a monomer or modifying agent in the development of specialized polymers and advanced materials with unique properties.
• Analytical Reference Standard Production: Critical for manufacturing high-purity certified reference materials (CRMs) used in quantitative analysis.
• Organic Synthesis Research: A versatile acyl chloride reagent for Friedel-Crafts acylation, esterification, and amide bond formation in academic and industrial R&D laboratories.

Basic Information

Product Name	Butyryl-2,2-D2 Chloride
CAS No.	90587-10-3
Molecular Formula	C4H5D2ClO
Molecular Weight	108.56 g/mol
Synonyms	Butanoyl-2,2-d2 chloride; Butyric-2,2-d2 acid chloride; Deuterated butyryl chloride; 2,2-Dideuteriobutanoic acid chloride; 1-(Chloroformyl)-1,1-dideuteriopropane; n-Butyryl-2,2-d2 chloride; Propane-1,1-d2-1-carbonyl chloride
EINECS	Contact for details

Quality Control

Our Butyryl-2,2-D2 Chloride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including NMR, GC, and GC-MS, to confirm isotopic enrichment, chemical purity, and identity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and moisture-sensitive nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Deuterium Enrichment (NMR)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.