Description

2-(4-Aminophenyl)Isothiazolidine 1,1-Dioxide is a specialized organic compound featuring a sulfonamide core linked to an aniline moiety, making it a valuable synthetic intermediate. This compound matters for its role in constructing complex molecules, particularly in pharmaceutical research and development. It is primarily needed by fine chemical manufacturers and R&D laboratories engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing sulfonamide-based pharmacophores.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides where the isothiazolidine dioxide scaffold can impart specific biological activity.
• Material Science: Potential monomer or additive in the production of specialized polymers, resins, or coatings with enhanced properties.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization, enabling the creation of libraries of compounds for high-throughput screening in drug discovery.
• Bioconjugation & Probe Development: The reactive amino group allows for coupling to biomolecules or fluorescent tags, useful in diagnostic and biochemical research applications.

Basic Information

Product Name	2-(4-Aminophenyl)Isothiazolidine 1,1-Dioxide
CAS No.	90556-91-5
Molecular Formula	C9H12N2O2S
Molecular Weight	212.27 g/mol
Synonyms	4-(1,1-Dioxidoisothiazolidin-2-yl)aniline; 2-(4-Aminophenyl)-1,2-thiazolidine 1,1-Dioxide; 2-(p-Aminophenyl)isothiazolidine 1,1-Dioxide; 4-(1,1-Dioxo-1,2-thiazolidin-2-yl)benzenamine; Benzenamine, 4-(1,1-dioxido-2-isothiazolidinyl)-; 2-(4-Amino-phenyl)-isothiazolidine 1,1-dioxide; 90556-91-5; 2-(4-Aminophenyl)thiazolidine 1,1-Dioxide
EINECS	Contact for details

Quality Control

Our 2-(4-Aminophenyl)Isothiazolidine 1,1-Dioxide is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, and we support custom purity requirements for specific applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.