Description

1,10-Phenanthroline-D8 is a deuterated derivative of the classic heterocyclic chelating agent, 1,10-phenanthroline, where eight hydrogen atoms are replaced by deuterium. This isotopic labeling is critical for applications requiring high sensitivity and specificity, such as advanced analytical techniques and mechanistic studies. It is an essential reagent for researchers and industries focused on analytical chemistry, pharmaceutical development, and materials science, where precise molecular tracking is paramount.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a stable isotope-labeled internal standard in LC-MS and GC-MS for the accurate quantification of 1,10-phenanthroline and related compounds in complex matrices.
• Mechanistic Reaction Studies: Employed in kinetic and mechanistic investigations, including isotope effect studies, to elucidate reaction pathways in catalysis and organic synthesis.
• Pharmaceutical Research & Metabolism: Serves as a tracer in drug metabolism and pharmacokinetics (DMPK) studies to monitor the absorption, distribution, metabolism, and excretion of phenanthroline-based molecules.
• Analytical Method Development: Essential for developing and validating highly sensitive and specific analytical methods in environmental, food, and clinical testing laboratories.
• NMR Spectroscopy Solvent & Reagent: Utilized as a deuterated shift reagent or in deuterated solvent systems for Nuclear Magnetic Resonance (NMR) spectroscopy.
• Materials Science Research: Applied in the study of photophysical properties and energy transfer mechanisms in novel luminescent materials and metal-organic frameworks (MOFs).

Basic Information

Product Name	1,10-Phenanthroline-D8
CAS No.	90412-47-8
Molecular Formula	C12D8N2
Molecular Weight	196.27 g/mol
Synonyms	Deuterated 1,10-Phenanthroline; 1,10-Phenanthroline-d8; 4,5,6,7-Tetradeutero-1,10-phenanthroline; Perdeutero-1,10-phenanthroline; o-Phenanthroline-d8; NSC 33971-d8; Phen-d8; Deuterated o-Phenanthroline
EINECS	Contact for details

Quality Control

Our 1,10-Phenanthroline-D8 is manufactured under strict quality protocols to ensure high isotopic purity and chemical integrity, meeting the stringent requirements of research and analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment (D-atom %), chemical purity, and identity confirmation. We adhere to relevant industry standards to guarantee reliable and reproducible performance in your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-atom %)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.