Description

4,4',6-Trimethylangelicin CAS NO 90370-29-9 is a synthetically modified furanocoumarin derivative, a class of compounds known for their photobiological activity. This specific trimethylated analog is of significant interest in pharmaceutical research and development due to its potential as a key intermediate or active pharmaceutical ingredient (API). It is primarily utilized by research institutions and manufacturers in the life sciences sector focusing on photochemotherapy, dermatology, and novel drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel therapeutic agents, particularly those targeting skin conditions.
• Photochemotherapy Research: Investigated for its photosensitizing properties in PUVA (Psoralen plus UVA) therapy research for conditions like psoriasis and vitiligo.
• Biochemical Research: Used as a standard or probe in studies examining DNA intercalation, photoadduct formation, and enzyme inhibition mechanisms.
• Dermatological Product Development: A potential active ingredient in the R&D of topical formulations for targeted phototherapeutic treatments.
• Academic & Industrial R&D: Employed in chemical biology and medicinal chemistry programs to explore structure-activity relationships (SAR) within the psoralen family.

Basic Information

Product Name	4,4',6-Trimethylangelicin
CAS No.	90370-29-9
Molecular Formula	C14H12O4
Molecular Weight	244.24 g/mol
Synonyms	4,4',6-Trimethylangelicin; 4,4',6-Trimethyl-2H,8H-Benzo[1,2-b:3,4-b']difuran-2,8-dione; 2H,8H-Benzo[1,2-b:3,4-b']difuran-2,8-dione, 4,4',6-trimethyl-; 4,4',6-Trimethylpsoralen; Trimethylangelicin; Angelicin, 4,4',6-trimethyl-
EINECS	Contact for details

Quality Control

Our 4,4',6-Trimethylangelicin is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.