Description

Coumestrol CAS NO 479-13-0 is a naturally occurring organic compound classified as a phytoestrogen and a member of the coumestan family. It serves as a critical reference standard and active research compound due to its potent biological activity, particularly its interaction with estrogen receptors. This high-purity material is essential for researchers and manufacturers in the pharmaceutical, nutraceutical, and life science industries who require a reliable and well-characterized compound for analytical, developmental, and quality control applications.

Application

• Pharmaceutical Research & Development: Used as a reference standard and active pharmaceutical ingredient (API) intermediate in studies related to hormone-dependent conditions, cancer research, and metabolic disorders.
• Nutraceutical & Dietary Supplement Analysis: Employed as an analytical standard to quantify phytoestrogen content in soy products, legumes, and herbal supplements for quality assurance and labeling accuracy.
• Biochemical & Life Science Research: Serves as a key tool in molecular biology and endocrinology to study estrogen receptor (ER) signaling pathways, gene expression, and cellular mechanisms.
• Cosmeceutical Development: Investigated for potential applications in skincare formulations targeting aging and skin health due to its antioxidant and estrogenic properties.
• Veterinary & Animal Science: Used in research concerning reproductive health and endocrine function in livestock and other animals.
• Food Science & Safety: Applied in method development and validation for the detection and quantification of natural estrogens in the food chain and environmental samples.

Basic Information

Item	Detail
Product Name	Coumestrol
CAS No.	479-13-0
Molecular Formula	C15H8O5
Molecular Weight	268.22 g/mol
Synonyms	3,9-Dihydroxy-6H-benzofuro[3,2-c]chromen-6-one; 3,9-Dihydroxycoumestan; Coumestro; Counestrol; NSC 25945; Phytoestrogen Coumestrol; (6aR,11aR)-3,9-Dihydroxycoumestan; Benzofuran derivative
EINECS	207-536-1

Quality Control

Our Coumestrol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, identity confirmation by spectroscopic methods (IR, NMR), and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with our stringent specifications. We support research and production needs that may require adherence to specific pharmacopeial or internal standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and potency. Keep the container sealed in a dry environment to prevent any potential moisture uptake.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.