Description

4-Hydroxycoumarin is a key organic heterocyclic compound and a fundamental building block in medicinal and synthetic chemistry. Its importance lies in its role as the core structural moiety for a wide range of bioactive molecules, including anticoagulants and other pharmacologically active agents. This versatile intermediate is essential for manufacturers and R&D teams in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active ingredients or synthesize complex organic molecules.

Application

• Pharmaceutical Intermediate: Primary precursor for the synthesis of anticoagulant drugs like warfarin and related 4-hydroxycoumarin derivatives.
• Agrochemical Synthesis: Used in the production of certain rodenticides and as a building block for developing novel pesticides.
• Fine Chemical Production: Serves as a key starting material for various dyes, fluorescent whiteners, and specialty organic compounds.
• Biochemical Research: Utilized in laboratory studies to investigate enzyme inhibition, particularly of vitamin K epoxide reductase.
• Material Science: Investigated for use in the development of organic electronic materials and metal-chelating agents.

Basic Information

Product Name	4-Hydroxycoumarin
CAS No.	1076-38-6
Molecular Formula	C9H6O3
Molecular Weight	162.14 g/mol
Synonyms	4-Hydroxy-2H-chromen-2-one; 4-Hydroxy-1-benzopyran-2-one; 4-Hydroxy-2H-1-benzopyran-2-one; Hydroxycoumarin; 4-HC; NSC 38297; Benzo-2-pyrone-4-ol
EINECS	214-060-2

Quality Control

Our 4-Hydroxycoumarin is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing specifications such as assay, melting point, and impurity profile is provided with each shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Melting Point	206°C - 210°C
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.