Description

Columbianetin is a naturally occurring dihydroisocoumarin derivative, a key chemical entity of interest in advanced research and development. Its unique benzopyrone structure makes it a valuable reference standard and a promising scaffold for the synthesis of novel bioactive compounds. This high-purity material is essential for researchers and manufacturers in the pharmaceutical, nutraceutical, and fine chemical sectors, particularly those focused on natural product chemistry and drug discovery.

Application

• Pharmaceutical Research & Development: Serves as a critical reference standard and a lead compound for developing new therapeutic agents.
• Natural Product Isolation & Analysis: Used as a benchmark in the isolation, identification, and quantification of related compounds from botanical sources.
• Bioactivity Studies: Investigated for its potential pharmacological properties, including anti-inflammatory, antioxidant, and antimicrobial activities.
• Fine Chemical Synthesis: Acts as a versatile intermediate or precursor in the synthesis of more complex dihydroisocoumarin derivatives and analogs.
• Academic & Institutional Research: Employed in universities and research institutes for studies in organic chemistry, phytochemistry, and medicinal chemistry.
• Quality Control Laboratories: Utilized as an analytical standard to ensure the purity and consistency of botanical extracts and related products.

Basic Information

Product Name	Columbianetin
CAS No.	1147-29-1
Molecular Formula	C14H14O4
Molecular Weight	246.26 g/mol
Synonyms	Columbianetin; 3,4-Dihydro-8-hydroxy-3-(1-hydroxy-1-methylethyl)-6-methoxy-1H-2-benzopyran-1-one; 8-Hydroxy-3-(2-hydroxypropan-2-yl)-6-methoxy-3,4-dihydroisochromen-1-one; 6-Methoxy-8-hydroxy-3-(2-hydroxy-2-propyl)-3,4-dihydro-1H-2-benzopyran-1-one; Angelicin hydrate; 3,4-Dihydro-8-hydroxy-3-(2-hydroxy-2-propyl)-6-methoxy-1H-2-benzopyran-1-one
EINECS	Contact for details

Quality Control

Our Columbianetin is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards for research chemicals, and specifications can be tailored to meet specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.