Description

6,5'-Dimethylangelicin is a synthetically modified furanocoumarin derivative, structurally related to psoralen. This compound is of significant interest in photochemistry and pharmaceutical research due to its potential as a photosensitizer. It is primarily utilized by research institutions and pharmaceutical developers exploring photodynamic therapy (PDT), photochemotherapy, and as a biochemical tool for studying DNA intercalation and light-induced biological responses.

Application

• Photodynamic Therapy (PDT) Research: Investigated as a potential photosensitizing agent for the treatment of certain skin conditions and cancers.
• Photochemotherapy Studies: Used in academic and industrial research to study mechanisms of action for PUVA (Psoralen + UVA) therapy analogs.
• Biochemical Research: Serves as a tool compound for studying interactions with DNA, including intercalation and photo-crosslinking.
• Organic Synthesis Intermediate: Acts as a key building block for the synthesis of more complex furanocoumarin derivatives with tailored properties.
• Photobiology Studies: Employed in research to understand cellular responses to UVA light and the generation of reactive oxygen species.

Basic Information

Product Name	6,5'-Dimethylangelicin
CAS No.	90370-11-9
Molecular Formula	C15H12O4
Molecular Weight	256.25 g/mol
Synonyms	6,5'-Dimethylangelicin; 6,5'-Dimethyl-2H-furo[2,3-h][1]benzopyran-2-one; 6,5'-Dimethylpsoralen (derivative); 6,5'-Dimethylfurocoumarin; Angelicin, 6,5'-dimethyl-; 6,5'-Dimethyl-angelicin; 6,5'-Dimethyl-2-oxo-2H-furo[2,3-h]chromene
EINECS	Contact for details

Quality Control

Our 6,5'-Dimethylangelicin is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, MS) for structural confirmation, to ensure high chemical integrity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.