Description

(-)-Indolactam V CAS NO 90365-57-4 is a potent and selective protein kinase C (PKC) activator, serving as a critical biochemical tool for studying cellular signaling pathways. Its high biological activity makes it invaluable for pharmaceutical research and development, particularly in oncology and neuroscience. This compound is essential for researchers in academic institutions, biotechnology firms, and pharmaceutical companies investigating PKC-mediated processes, drug discovery, and molecular pharmacology.

Application

• Biochemical Research: A key tool compound for activating Protein Kinase C (PKC) isoforms in cell-based and in vitro assays to study signal transduction.
• Drug Discovery & Pharmacology: Used in high-throughput screening and target validation studies for developing novel therapeutics targeting PKC pathways.
• Oncology Research: Employed to investigate the role of PKC in tumor promotion, cell proliferation, and apoptosis in cancer cell lines.
• Neuroscience Studies: Applied in research on neurotransmitter release, synaptic plasticity, and neuronal differentiation where PKC signaling is involved.
• Toxicology & Safety Assessment: Serves as a reference standard in studies examining the mechanisms of tumor promoters and environmental toxins.
• Academic & Institutional Research: A fundamental reagent for basic science exploring second messenger systems and cellular regulation.

Basic Information

Product Name	(-)-Indolactam V
CAS No.	90365-57-4
Molecular Formula	C₁₉H₂₆N₄O₂
Molecular Weight	342.44 g/mol
Synonyms	(-)-Indolactam V; Indolactam V; Teleocidin V; L-156,602; (3S,4aR,10bS)-8,9,10,10a-Tetrahydro-4a,10b-epidiminoethano-3-(1H-indol-3-ylmethyl)-4aH-azepino[3,4-b]indol-5(6H)-one; PKC Activator I
EINECS	Contact for details

Quality Control

Our (-)-Indolactam V is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemicals and can provide material suitable for research use under GMP-like conditions upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated under an inert atmosphere. Allow the vial to warm to room temperature in a dry environment before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Biological Activity (PKC Activation)	Conforms to reference standard

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.