Description

(R)-(-)-4-Phenyl-2-Oxazolidinone is a high-purity chiral auxiliary and synthetic intermediate of significant importance in asymmetric organic synthesis. Its value lies in its ability to induce high enantioselectivity in a variety of chemical transformations, enabling the production of single-enantiomer compounds. This product is essential for research and development chemists and production units in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality chiral building blocks.

Application

• Chiral Auxiliary in Asymmetric Synthesis: Widely used to control stereochemistry in aldol reactions, alkylations, and Diels-Alder reactions.
• Pharmaceutical Intermediate: Key building block in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), including β-lactam antibiotics and other therapeutics.
• Agrochemical Synthesis: Employed in the production of chiral pesticides and herbicides where specific stereochemistry is crucial for activity.
• Catalyst and Ligand Preparation: Serves as a precursor for the synthesis of novel chiral catalysts and ligands used in homogeneous catalysis.
• Academic and Industrial R&D: A fundamental reagent for methodological development in organic chemistry and process chemistry optimization.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, flavors, and fragrances requiring precise chiral control.

Basic Information

Product Name	(R)-(-)-4-Phenyl-2-Oxazolidinone
CAS No.	90319-52-1
Molecular Formula	C9H9NO2
Molecular Weight	163.17 g/mol
Synonyms	(R)-4-Phenyl-2-oxazolidinone; (R)-(-)-4-Phenyl-2-oxazolidinone; (4R)-4-Phenyl-1,3-oxazolidin-2-one; (R)-4-Phenyloxazolidin-2-one; Evans Auxiliary (R)-form; (R)-BOZ; (R)-Phenyloxazolidinone
EINECS	Contact for details

Quality Control

Our (R)-(-)-4-Phenyl-2-Oxazolidinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	88 - 92 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.