Description

3-Thiophenecarbonitrile, 2-Amino-4-Chloro- is a high-purity, multi-functional heterocyclic building block with the CAS registry number 90312-20-2. This compound is valued for its unique molecular architecture, which combines a reactive nitrile group and a halogenated amino-thiophene core, making it a versatile intermediate for advanced synthesis. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, including active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Serves as a critical building block for developing new-generation herbicides, fungicides, and insecticides with improved efficacy.
• Material Science Research: Used in the development of organic semiconductors, conductive polymers, and non-linear optical (NLO) materials due to its electron-rich thiophene ring.
• Ligand and Catalyst Development: Employed to create specialized ligands for metal-catalyzed cross-coupling reactions and asymmetric synthesis.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing specialized dyes and functional pigments.
• Academic & Contract Research: Essential reagent for methodological studies and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	3-Thiophenecarbonitrile, 2-Amino-4-Chloro-
CAS No.	90312-20-2
Molecular Formula	C5H3ClN2S
Molecular Weight	158.61 g/mol
Synonyms	2-Amino-4-chlorothiophene-3-carbonitrile; 4-Chloro-2-aminothiophene-3-carbonitrile; 4-Chloro-2-amino-3-cyanothiophene; 2-Amino-4-chloro-3-thiophenecarbonitrile; 3-Cyano-4-chloro-2-aminothiophene; 4-Chloro-2-aminothiophene-3-carbonitrile; 2-Amino-4-chloro-thiophene-3-carbonitrile
EINECS	Contact for details

Quality Control

Every batch of 3-Thiophenecarbonitrile, 2-Amino-4-Chloro- is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.