Description

5-Acetyl-10,11-Dihydro-5H-Dibenz[B,F]Azepine Nitrate is a high-purity pharmaceutical intermediate and research chemical of significant commercial interest. This compound is valued for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in neurological and psychiatric research. It is essential for manufacturers and R&D laboratories in the pharmaceutical, biotechnology, and fine chemical sectors seeking reliable, high-quality raw materials for advanced synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of tricyclic antidepressant and neuroactive drug candidates.
• Neurological Research: Used in biochemical research to study receptor binding and neurological pathways.
• Organic Synthesis: Serves as a versatile building block for constructing complex dibenzazepine-based molecular frameworks.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Academic & Contract Research: Utilized in university and CRO settings for medicinal chemistry projects and novel compound library development.

Basic Information

Product Name	5-Acetyl-10,11-Dihydro-5H-Dibenz[B,F]Azepine Nitrate
CAS No.	90284-53-0
Molecular Formula	C16H14N2O3
Molecular Weight	282.30 g/mol
Synonyms	5-Acetyl-10,11-dihydro-5H-dibenzo[b,f]azepine nitrate; 10,11-Dihydro-5-acetyl-5H-dibenzo[b,f]azepine nitrate; 5-Acetyliminodibenzyl nitrate; Imipramine N-oxide nitrate derivative; 5H-Dibenz[b,f]azepine-5-acetic acid, 10,11-dihydro-, nitrate; Nitrate salt of 5-Acetyliminostilbene
EINECS	Contact for details

Quality Control

Our 5-Acetyl-10,11-Dihydro-5H-Dibenz[B,F]Azepine Nitrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical R&D and synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.