Description

5-Thiophen-2-Yl-Isoxazole-3-Carboxylic Acid Hydrazide is a high-purity heterocyclic building block and key synthetic intermediate of significant interest in advanced organic chemistry. Its unique molecular architecture, featuring fused thiophene and isoxazole rings with a reactive hydrazide moiety, makes it a versatile precursor for constructing complex pharmacophores. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients targeting a range of biological pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of novel drug candidates, particularly in the development of anti-inflammatory, antimicrobial, and central nervous system (CNS) active compounds.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Chemical Biology Probe: Employed in academic and industrial research to create molecular probes for studying enzyme function and biological pathways due to its reactive hydrazide group.
• Material Science Precursor: Acts as a monomer or functionalizing agent in the synthesis of specialized polymers and organic electronic materials.
• Custom Synthesis & Contract Manufacturing: A key starting material for fine chemical manufacturers offering bespoke synthesis services for clients in life sciences.

Basic Information

Item	Details
Product Name	5-Thiophen-2-Yl-Isoxazole-3-Carboxylic Acid Hydrazide
CAS No.	90004-25-4
Molecular Formula	C8H7N3O2S
Molecular Weight	209.23 g/mol
Synonyms	5-(Thiophen-2-yl)isoxazole-3-carbohydrazide; 5-(2-Thienyl)-3-isoxazolecarboxylic acid hydrazide; 5-(Thiophen-2-yl)-1,2-oxazole-3-carbohydrazide; 90004-25-4; Thiophene-isoxazole hydrazide; Isoxazole-3-carboxylic acid, 5-(2-thienyl)-, hydrazide
EINECS	Contact for details

Quality Control

Every batch of 5-Thiophen-2-Yl-Isoxazole-3-Carboxylic Acid Hydrazide is manufactured under strict quality management protocols. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including HPLC for purity and identity confirmation, is performed. A detailed Certificate of Analysis (COA) documenting batch-specific results is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.