Description

Iodomethane-D1 is a deuterated isotopologue of iodomethane, where a hydrogen atom is replaced by a deuterium atom, specifically at the methyl position. This isotopic labeling is critical for applications requiring precise molecular tracking, as it provides a distinct spectroscopic signature without significantly altering the chemical's reactivity. It is an essential reagent for researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors who require stable isotope-labeled compounds for advanced studies.

Application

• Pharmaceutical Research & Development: Used as a deuterium-labeled building block in the synthesis of Active Pharmaceutical Ingredients (APIs) for metabolism studies, pharmacokinetic profiling, and internal standards in quantitative bioanalysis.
• Analytical Chemistry: Serves as a critical internal standard in Gas Chromatography-Mass Spectrometry (GC-MS) and Liquid Chromatography-Mass Spectrometry (LC-MS) to ensure accurate quantification of iodomethane and related compounds.
• Mechanistic Studies: Employed in reaction mechanism elucidation and kinetic isotope effect (KIE) studies to understand chemical pathways and transition states.
• Agrochemical Development: Utilized in the synthesis of labeled pesticide and herbicide analogs for environmental fate studies, residue analysis, and degradation pathway tracking.
• NMR Spectroscopy: Acts as a useful solvent or reagent in Nuclear Magnetic Resonance (NMR) spectroscopy due to its distinct deuterium signal.
• Material Science: Can be used in the synthesis of specialty polymers or organic electronic materials where isotopic labeling is required to study structure-property relationships.

Basic Information

Product Name	Iodomethane-D1
CAS No.	992-96-1
Molecular Formula	CD2HI
Molecular Weight	143.94 g/mol
Synonyms	Deuterated Iodomethane; Methyl-d2 Iodide; (Methyl-d2)-Iodide; Iodomethane-2H2; Iodomethane-d2; Methyl Iodide-d2; CD2HI; Methyl-d2 Iodide-13C (common variant listing)
EINECS	Contact for details

Quality Control

Our Iodomethane-D1 is produced and tested under stringent quality management systems. Each batch undergoes comprehensive analysis to ensure high chemical purity and isotopic enrichment, typically exceeding 99% chemical purity and 98 atom % D. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, isotopic purity, and impurity profiles via validated methods including GC, NMR, and MS.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place, away from heat sources and incompatible materials. Due to its highly volatile nature, containers should be kept tightly sealed and under appropriate conditions (typically 2-8°C or as specified on the label) to maintain stability and prevent loss.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (GC)	≥ 99.0%
Isotopic Purity (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.