Description

1H-Isoindol-1-One, 3-(4-Chlorophenyl)-2,3-Dihydro-3-Hydroxy- is a versatile chiral building block and synthetic intermediate characterized by its isoindolinone core structure with a chlorophenyl substituent. This compound matters for its role in facilitating the synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and advanced materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of potential drug candidates, including central nervous system (CNS) agents and enzyme inhibitors.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, or plant growth regulators with specific stereochemical requirements.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands for asymmetric catalysis and organometallic complexes.
• Material Science Research: Intermediate in the synthesis of specialty polymers, dyes, or organic electronic materials.
• Academic & Contract Research: Serves as a valuable substrate for methodological studies in organic synthesis and medicinal chemistry.
• Fine Chemical Production: Employed in the multi-step synthesis of high-value, complex fine chemicals for various industrial applications.

Basic Information

Product Name	1H-Isoindol-1-One, 3-(4-Chlorophenyl)-2,3-Dihydro-3-Hydroxy-
CAS No.	956-92-3
Molecular Formula	C14H10ClNO2
Molecular Weight	259.69 g/mol
Synonyms	3-(4-Chlorophenyl)-3-hydroxyisoindolin-1-one; 3-Hydroxy-3-(4-chlorophenyl)isoindolin-1-one; 3-(p-Chlorophenyl)-3-hydroxy-2,3-dihydro-1H-isoindol-1-one; 1H-Isoindol-1-one, 3-(4-chlorophenyl)-2,3-dihydro-3-hydroxy-; (3RS)-3-(4-Chlorophenyl)-3-hydroxyisoindolin-1-one; (±)-3-(4-Chlorophenyl)-3-hydroxyisoindolin-1-one; rac-3-(4-Chlorophenyl)-3-hydroxyisoindolin-1-one
EINECS	Contact for details

Quality Control

Our 1H-Isoindol-1-One, 3-(4-Chlorophenyl)-2,3-Dihydro-3-Hydroxy- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data, including HPLC purity, chiral purity (if applicable), and identification by IR and NMR. Our quality commitment supports cGMP and ISO standards for reliable use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.