Description

3-(Trifluoromethyl)Thiophenol is a versatile organosulfur and organofluorine building block characterized by a thiol (-SH) group attached to a trifluoromethyl-substituted benzene ring. This compound matters for its unique combination of high reactivity and the stability imparted by the fluorine atoms, making it a critical intermediate in advanced synthesis. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and material science industries for constructing complex molecules with enhanced properties.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly those requiring bioisosteric replacement or enhanced metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group improves efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Polymer and Material Science: Incorporated into monomers for high-performance polymers, liquid crystals, and organic electronic materials to modify solubility and electronic properties.
• Chemical Research & Development: A valuable reagent for exploring novel reaction pathways and creating compound libraries in medicinal and synthetic chemistry.

Basic Information

Product Name	3-(Trifluoromethyl)Thiophenol
CAS No.	937-00-8
Molecular Formula	C7H5F3S
Molecular Weight	178.17 g/mol
Synonyms	3-(Trifluoromethyl)benzenethiol; alpha,alpha,α-Trifluoro-m-toluenethiol; m-(Trifluoromethyl)thiophenol; 3-Trifluoromethylphenyl mercaptan; 3-Mercaptobenzotrifluoride; 1-Mercapto-3-(trifluoromethyl)benzene; Benzenethiol, 3-(trifluoromethyl)-; (3-Trifluoromethylphenyl)thiol
EINECS	213-328-4

Quality Control

Our production of 3-(Trifluoromethyl)Thiophenol adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.