Description

1-Methyl-2-Pyrrolidinone-D3 is a deuterated analog of the versatile polar aprotic solvent N-Methyl-2-pyrrolidone (NMP). This isotopically labeled compound is critical for applications requiring precise analytical tracking and reduced interference from proton signals. It is primarily utilized as a solvent and reagent in advanced research and development within the pharmaceutical, chemical, and material science industries.

Application

• NMR Spectroscopy: Used as a deuterated solvent for nuclear magnetic resonance (NMR) analysis, providing a lock signal and minimizing background proton interference in organic compound characterization.
• Pharmaceutical Research: Serves as a reaction medium or reagent in the synthesis and process development of deuterated active pharmaceutical ingredients (APIs) and drug metabolites.
• Chemical Synthesis: Employed as a specialty solvent in organic synthesis, particularly for reactions where isotopic labeling or kinetic isotope effect studies are required.
• Material Science: Used in the development and analysis of specialty polymers, resins, and electronic materials where deuterated solvents are necessary for specific analytical techniques.
• Analytical Chemistry: Functions as a mobile phase component or sample solvent in advanced chromatographic and mass spectrometric methods.

Basic Information

Product Name	1-Methyl-2-Pyrrolidinone-D3
CAS No.	933-86-8
Molecular Formula	C5H6D3NO
Molecular Weight	100.15 g/mol
Synonyms	N-Methyl-2-pyrrolidinone-d3; NMP-d3; 1-Methyl-2-pyrrolidone-d3; N-Methyl-2-pyrrolidone-d3; Deuterated N-Methylpyrrolidone; N-Methylpyrrolidinone-d3; 2-Pyrrolidinone, 1-methyl-d3; Methylpyrrolidinone-d3
EINECS	Contact for details

Quality Control

Our 1-Methyl-2-Pyrrolidinone-D3 is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR, GC, and Karl Fischer titration, to ensure high isotopic purity and chemical purity. Certificates of Analysis (COA) detailing isotopic enrichment (typically >99 atom % D), chemical assay, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Isotopic Purity (NMR)	≥ 99 atom % D
Assay (GC)	≥ 99.0%
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.