Description

(Iodoethynyl)Benzene CAS NO 932-88-7 is a specialized organoiodine compound featuring a reactive ethynyl group directly bonded to an iodine atom on a benzene ring. This unique structure makes it a valuable building block in advanced organic synthesis, particularly for cross-coupling reactions and the construction of complex molecular architectures. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries seeking to introduce iodine or acetylene functionalities with precision.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for Sonogashira and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators that require iodinated aromatic cores.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of conjugated polymers, organic semiconductors, and advanced organic frameworks (MOFs/COFs).
• Ligand and Catalyst Preparation: Employed for the synthesis of specialized phosphine or N-heterocyclic carbene (NHC) ligands containing iodophenyl groups.
• Radiopharmaceutical Precursor: Potential use as a precursor for labeling compounds with radioisotopes of iodine for diagnostic imaging or therapy.
• Organic Synthesis Building Block: A versatile reagent for introducing the phenylethynyl iodide moiety into target molecules for further functionalization.

Basic Information

Product Name	(Iodoethynyl)Benzene
CAS No.	932-88-7
Molecular Formula	C8H5I
Molecular Weight	228.03 g/mol
Synonyms	1-Iodo-2-phenylethyne; 2-Phenylethynyl Iodide; Ethynylbenzene, iodo-; Iodophenylacetylene; (Iodoethynyl)benzene; Phenylethynyl iodide; (Iodoethynyl)benzol; Iodoethynylbenzene
EINECS	Contact for details

Quality Control

Our (Iodoethynyl)Benzene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is analyzed using advanced techniques including GC, HPLC, and NMR to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature, prolonged exposure to light should be avoided. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.