Description

4-Bromopyrole-2-Carboxaldehyde is a versatile brominated heterocyclic building block of significant importance in advanced organic synthesis. Its reactive aldehyde and bromine functional groups make it a critical precursor for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, serving as a key intermediate in the development of active compounds and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of pyrrole-containing drug candidates, including kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides that leverage the pyrrole moiety for biological activity.
• Material Science: Serves as a building block for conductive polymers, organic semiconductors, and advanced organic frameworks (MOFs/COFs).
• Chemical Research: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to introduce the pyrrole-aldehyde unit into more complex structures.
• Dye and Pigment Manufacturing: Acts as a precursor for synthesizing specialized heterocyclic dyes and pigments.
• Ligand Synthesis: Useful for preparing novel chelating ligands in coordination chemistry and catalysis.

Basic Information

Product Name	4-Bromopyrole-2-Carboxaldehyde
CAS No.	931-33-9
Molecular Formula	C5H4BrNO
Molecular Weight	173.99 g/mol
Synonyms	4-Bromo-1H-pyrrole-2-carboxaldehyde; 4-Bromo-2-formylpyrrole; 2-Formyl-4-bromopyrrole; 4-Bromopyrrole-2-aldehyde; 4-Bromo-2-pyrrolecarboxaldehyde; 1H-Pyrrole-2-carboxaldehyde, 4-bromo-; 4-Bromopyrrol-2-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 4-Bromopyrole-2-Carboxaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.