Description

Heptamethyldisilazane is a versatile organosilicon compound widely used as a silylating agent and protecting group reagent. Its primary value lies in its ability to efficiently introduce the trimethylsilyl (TMS) group, modifying the properties of target molecules for synthesis, analysis, and material science. This high-purity chemical is essential for manufacturers and researchers in the pharmaceutical, semiconductor, and specialty chemical industries, where precise surface modification and functional group protection are critical.

Application

• Pharmaceutical Synthesis: Used as a silylating agent to protect reactive functional groups (e.g., -OH, -NH) during multi-step synthesis of active pharmaceutical ingredients (APIs).
• Semiconductor Manufacturing: Employed in vapor phase deposition processes as a precursor for silicon nitride (SiN) or silicon oxide (SiOx) thin films on wafers.
• Surface Modification: Functionalizes silica, glass, and other oxide surfaces to create hydrophobic or specific reactive interfaces.
• Gas Chromatography (GC): Acts as a derivatization reagent to improve the volatility and thermal stability of polar compounds for analysis.
• Polymer & Resin Production: Serves as a blocking agent or chain terminator in the synthesis of silicones and other specialty polymers.
• Catalyst & Reagent Preparation: Used to prepare moisture-sensitive catalysts and reagents by silylating reactive sites.

Basic Information

Product Name	Heptamethyldisilazane
CAS No.	920-68-3
Molecular Formula	C7H21NSi2
Molecular Weight	175.43 g/mol
Synonyms	1,1,1,3,3,3-Hexamethyldisilazane; HMDS; Bis(trimethylsilyl)amine; Hexamethyldisilazane; N,N-Bis(trimethylsilyl)amine; 1,1,1-Trimethyl-N-(trimethylsilyl)silanamine; HMDS; TMS2NH
EINECS	213-048-4

Quality Control

Our Heptamethyldisilazane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for demanding applications. Each lot undergoes comprehensive analytical testing, including Gas Chromatography (GC) for assay and impurity profiling. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms
Assay (GC)	≥ 99.0%
Water Content (KF)	≤ 0.1%
Chloride (as Cl)	≤ 10 ppm
Refractive Index (n20/D)	1.407 - 1.409
Density (20°C)	0.774 - 0.778 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.