Description

2-Chloro-2-Methylpropane-D9 is a deuterated analog of tert-butyl chloride, serving as a crucial isotopically labeled reagent. This compound is essential for advanced analytical and synthetic chemistry, providing a stable, non-radioactive isotopic tracer. It is primarily utilized by researchers and manufacturers in pharmaceutical development, agrochemical research, and material science for applications such as reaction mechanism elucidation, metabolic studies, and as an internal standard in mass spectrometry.

Application

• Pharmaceutical Research & Development: Used as a deuterated building block in the synthesis of labeled drug candidates for pharmacokinetic and metabolic studies (ADME).
• Analytical Chemistry: Serves as a critical internal standard in Gas Chromatography-Mass Spectrometry (GC-MS) and Liquid Chromatography-Mass Spectrometry (LC-MS) for accurate quantification.
• Mechanistic Studies: Employed as a tracer in organic reaction mechanisms to study pathways and kinetics in nucleophilic substitution reactions.
• Agrochemical Research: Utilized in the development and analysis of deuterated pesticides or herbicides to study environmental fate and degradation.
• Material Science: Acts as a precursor or labeling agent in the synthesis of specialized polymers or advanced materials where deuterium incorporation is required.
• NMR Spectroscopy: Used as a solvent or reagent in Nuclear Magnetic Resonance (NMR) spectroscopy due to its deuterium content, aiding in solvent signal suppression.

Basic Information

Product Name	2-Chloro-2-Methylpropane-D9
CAS No.	918-20-7
Molecular Formula	C4D9Cl
Molecular Weight	108.64 g/mol
Synonyms	tert-Butyl chloride-d9; (1,1-Dimethylethyl)-d9 chloride; 2-Chloro-2-methylpropane-d9; tert-Butyl-d9 chloride; Deuterated tert-butyl chloride; Perdeuterated tert-butyl chloride; 2-Methyl-2-chloropropane-d9; Chlorotrimethylmethane-d9
EINECS	Contact for details

Quality Control

Our 2-Chloro-2-Methylpropane-D9 is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and isotopic enrichment, with specifications typically meeting or exceeding industry standards for labeled compounds. Certificates of Analysis (COA) detailing parameters such as assay (by GC or NMR), isotopic purity (D-enrichment), and impurity profile are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place, away from heat sources and incompatible materials such as strong bases. Due to its highly volatile nature, ensure containers are securely sealed. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR/NMR)	Conforms to structure
Assay (GC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.