Description

T-Butyl Hypoiodite is a specialized organoiodine compound used as a versatile reagent in organic synthesis. Its primary value lies in its ability to act as a source of the hypoiodite radical, facilitating key transformations such as oxidative functionalization and cyclization reactions. This high-purity intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel compounds and synthetic pathways.

Application

• Pharmaceutical Intermediate Synthesis: Used in the construction of complex molecular scaffolds, particularly in the synthesis of iodine-containing drug candidates and active pharmaceutical ingredients (APIs).
• Oxidative Cyclization Reactions: Facilitates the formation of oxygen- and nitrogen-containing heterocycles, which are common structural motifs in many bioactive molecules.
• Radical Chemistry Research: Serves as a critical reagent in academic and industrial R&D for studying and applying new radical-based synthetic methodologies.
• Fine Chemical Production: Employed in the precise, small-scale synthesis of high-value specialty chemicals and advanced materials.
• Polymer Modification: Can be used to introduce iodine functional groups into polymer chains for subsequent cross-linking or further derivatization.

Basic Information

Product Name	T-Butyl Hypoiodite
CAS No.	917-97-5
Molecular Formula	C4H9IO
Molecular Weight	200.02 g/mol
Synonyms	tert-Butyl Hypoiodite; 2-Methyl-2-propyl Hypoiodite; Hypoiodous Acid tert-Butyl Ester; tert-C4H9OI; TBHI
EINECS	Contact for details

Quality Control

Our T-Butyl Hypoiodite is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and industrial applications. Each lot is analyzed using advanced techniques including NMR, IR, and GC/HPLC to verify identity and assay. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and easily oxidized nature, this material must be stored under an inert atmosphere (e.g., nitrogen or argon) at recommended temperatures between 2°C and 8°C. Handle and open containers only in a controlled, moisture-free environment to prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 95.0%
Purity (NMR)	≥ 97.0%
Related Substances (HPLC)	≤ 3.0% total
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.