Description

2-Amino-4-(3-Bromo-4-Methoxyphenyl)-5-Thiazolecarboxylic Acid Ethyl Ester is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters because it provides a versatile scaffold for constructing complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new compounds with targeted biological activities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or possessing anti-inflammatory properties.
• Agrochemical Research: Used as a core structure for developing new generation herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probe: Serves as a building block for creating molecular probes to study biological pathways and protein functions.
• Material Science: Potential intermediate for synthesizing advanced organic electronic materials or liquid crystals due to its conjugated thiazole system.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific research and scale-up projects.
• Academic & Institutional Research: Utilized in university and government labs for fundamental research in heterocyclic and medicinal chemistry.

Basic Information

Product Name	2-Amino-4-(3-Bromo-4-Methoxyphenyl)-5-Thiazolecarboxylic Acid Ethyl Ester
CAS No.	899363-48-5
Molecular Formula	C13H13BrN2O3S
Molecular Weight	357.22 g/mol
Synonyms	Ethyl 2-Amino-4-(3-bromo-4-methoxyphenyl)thiazole-5-carboxylate; 5-Thiazolecarboxylic acid, 2-amino-4-(3-bromo-4-methoxyphenyl)-, ethyl ester; 2-Amino-4-(3-bromo-4-methoxyphenyl)-1,3-thiazole-5-carboxylic acid ethyl ester; 899363-48-5; AKOS025311324; BRD-K77933360-001-01-1; SCHEMBL15506227; CTK8G7231
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-4-(3-Bromo-4-Methoxyphenyl)-5-Thiazolecarboxylic Acid Ethyl Ester undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, and we provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay purity and impurity profiles. Specifications can be developed to meet specific client requirements for research or development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.