Description

2-Amino-4-(3-Chloro-4-Methoxyphenyl)-5-Thiazolecarboxylic Acid Ethyl Ester is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique thiazole core enables the creation of molecules with targeted biological activity. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to innovate and scale new chemical entities.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting infectious diseases, inflammation, and oncology.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its bioactive thiazole scaffold.
• Chemical Synthesis: Serves as a versatile precursor for constructing complex heterocyclic compounds in academic and industrial research laboratories.
• Material Science: Potential applications in the development of specialty polymers, dyes, and functional materials due to its aromatic and heteroatom-rich structure.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects under cGMP conditions.

Basic Information

Product Name	2-Amino-4-(3-Chloro-4-Methoxyphenyl)-5-Thiazolecarboxylic Acid Ethyl Ester
CAS No.	899362-91-5
Molecular Formula	C13H13ClN2O3S
Molecular Weight	312.77 g/mol
Synonyms	Ethyl 2-Amino-4-(3-chloro-4-methoxyphenyl)thiazole-5-carboxylate; 5-Thiazolecarboxylic acid, 2-amino-4-(3-chloro-4-methoxyphenyl)-, ethyl ester; 2-Amino-4-(3-chloro-4-methoxyphenyl)-1,3-thiazole-5-carboxylic acid ethyl ester; 899362-91-5; AKOS005258781; Ethyl 2-amino-4-(3-chloro-4-methoxyphenyl)-1,3-thiazole-5-carboxylate
EINECS	Contact for details

Quality Control

Our 2-Amino-4-(3-Chloro-4-Methoxyphenyl)-5-Thiazolecarboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to supply chain reliability and documentation transparency supports your regulatory and process development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed in a dry environment. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.