Description

2-Amino-4-(3,4,5-Trimethoxyphenyl)-5-thiazolecarboxylic acid ethyl ester is a high-purity, specialized organic compound featuring a thiazole core substituted with a trimethoxyphenyl group. This molecule is a critical pharmaceutical intermediate and a versatile building block in advanced organic synthesis. It is primarily sought by research institutions and fine chemical manufacturers engaged in the development of novel bioactive molecules, particularly in medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting specific enzymatic pathways.
• Medicinal Chemistry Research: Serves as a core scaffold for designing and synthesizing new chemical entities (NCEs) for biological screening and structure-activity relationship (SAR) studies.
• Organic Synthesis Building Block: Used in multi-step synthesis to construct more complex heterocyclic systems due to its reactive amino and ester functional groups.
• Agrochemical Research: Potential intermediate in the development of novel herbicides or fungicides, leveraging its unique aromatic-thiazole structure.
• Material Science: Investigated as a monomer or precursor for specialty polymers and advanced organic materials with specific electronic properties.

Basic Information

Product Name	2-Amino-4-(3,4,5-Trimethoxyphenyl)-5-Thiazolecarboxylic Acid Ethyl Ester
CAS No.	899354-59-7
Molecular Formula	C15H18N2O5S
Molecular Weight	338.38 g/mol
Synonyms	Ethyl 2-amino-4-(3,4,5-trimethoxyphenyl)-1,3-thiazole-5-carboxylate; 5-Thiazolecarboxylic acid, 2-amino-4-(3,4,5-trimethoxyphenyl)-, ethyl ester; 2-Amino-4-(3,4,5-trimethoxyphenyl)thiazole-5-carboxylic acid ethyl ester; 4-(3,4,5-Trimethoxyphenyl)-2-amino-5-thiazolecarboxylic acid ethyl ester; TAE; ATTE
EINECS	Contact for details

Quality Control

Our 2-Amino-4-(3,4,5-Trimethoxyphenyl)-5-thiazolecarboxylic acid ethyl ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for pharmaceutical applications, and specifications can be tailored to meet specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert gas purging to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.