Description

2-Amino-4-[4-(1-Methylethyl)Phenyl]-5-Thiazolecarboxylic Acid Ethyl Ester is a high-purity, specialized organic intermediate featuring a thiazole core with an isopropylphenyl substituent. This compound is valued for its role as a critical building block in the synthesis of advanced pharmaceutical and agrochemical active ingredients. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Synthesis: Serves as a core scaffold for developing new-generation herbicides and fungicides with enhanced efficacy and selectivity.
• Material Science Research: Used in the development of organic semiconductors and advanced polymers due to its electron-rich thiazole structure.
• Chemical Biology Probes: Employed in the creation of fluorescent tags and molecular probes for biochemical research and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Item	Details
Product Name	2-Amino-4-[4-(1-Methylethyl)Phenyl]-5-Thiazolecarboxylic Acid Ethyl Ester
CAS No.	899352-59-1
Molecular Formula	C15H18N2O2S
Molecular Weight	290.38 g/mol
Synonyms	Ethyl 2-Amino-4-(4-isopropylphenyl)thiazole-5-carboxylate; 2-Amino-4-(p-isopropylphenyl)-5-thiazolecarboxylic Acid Ethyl Ester; 5-Thiazolecarboxylic acid, 2-amino-4-[4-(1-methylethyl)phenyl]-, ethyl ester; 4-(4-Isopropylphenyl)-2-amino-5-thiazolecarboxylic acid ethyl ester; 2-Amino-4-(4-isopropylphenyl)-1,3-thiazole-5-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 2-Amino-4-[4-(1-Methylethyl)Phenyl]-5-Thiazolecarboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure full traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.