Description

2-Amino-4-(3,4-Dimethylphenyl)-5-thiazolecarboxylic acid ethyl ester is a specialized organic intermediate of significant interest in advanced chemical synthesis. This compound matters for its role as a key building block in the development of complex heterocyclic molecules, particularly in pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel thiazole-based drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole core.
• Material Science: Acts as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic electronic materials.
• Chemical Biology: Employed as a molecular probe or scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for fundamental research in heterocyclic chemistry and method development.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) producing bespoke fine chemicals for client-specific projects.

Basic Information

Product Name	2-Amino-4-(3,4-Dimethylphenyl)-5-thiazolecarboxylic Acid Ethyl Ester
CAS No.	899352-57-9
Molecular Formula	C14H16N2O2S
Molecular Weight	276.35 g/mol
Synonyms	Ethyl 2-Amino-4-(3,4-dimethylphenyl)thiazole-5-carboxylate; 5-Thiazolecarboxylic acid, 2-amino-4-(3,4-dimethylphenyl)-, ethyl ester; 2-Amino-4-(3,4-dimethylphenyl)-1,3-thiazole-5-carboxylic acid ethyl ester; 4-(3,4-Dimethylphenyl)-2-amino-5-thiazolecarboxylic acid ethyl ester; AKOS BRN 1258; ZINC000257019789; A1/002032/ALDRICH
EINECS	Contact for details

Quality Control

Our 2-Amino-4-(3,4-Dimethylphenyl)-5-thiazolecarboxylic acid ethyl ester is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure consistency and compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.