Description

2-Amino-4-[4-(1,1-Dimethylethyl)Phenyl]-5-Thiazolecarboxylic Acid Ethyl Ester is a high-value, specialized organic intermediate featuring a thiazole core substituted with an amino group and a tert-butylphenyl moiety. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceutical agents and agrochemicals, where its unique structure imparts specific biological activity and physicochemical properties. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, or infectious diseases.
• Agrochemical Research: Serves as a core scaffold for developing new generation herbicides, fungicides, or insecticides, leveraging the bioactivity of the thiazole ring.
• Material Science: Potential monomer or additive for creating specialized polymers with enhanced thermal stability or optical properties, attributed to the tert-butylphenyl group.
• Organic Synthesis Building Block: Used in academic and industrial R&D for constructing complex heterocyclic compounds via further functionalization of the amino and ester groups.
• Ligand Synthesis: Can be utilized to develop novel ligands for catalysis or metal-organic frameworks (MOFs) due to its nitrogen and oxygen donor atoms.

Basic Information

Product Name	2-Amino-4-[4-(1,1-Dimethylethyl)Phenyl]-5-Thiazolecarboxylic Acid Ethyl Ester
CAS No.	899352-47-7
Molecular Formula	C16H20N2O2S
Molecular Weight	304.41 g/mol
Synonyms	Ethyl 2-Amino-4-(4-tert-butylphenyl)thiazole-5-carboxylate; 4-(4-tert-Butylphenyl)-2-aminothiazole-5-carboxylic Acid Ethyl Ester; 2-Amino-4-(p-tert-butylphenyl)-5-thiazolecarboxylic Acid Ethyl Ester; 5-Thiazolecarboxylic acid, 2-amino-4-[4-(1,1-dimethylethyl)phenyl]-, ethyl ester; 4-(4-tert-Butylphenyl)-2-aminothiazole-5-carboxylate Ethyl Ester
EINECS	Contact for details

Quality Control

Our 2-Amino-4-[4-(1,1-Dimethylethyl)Phenyl]-5-Thiazolecarboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and away from moisture and direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.